FB2026_02 , released June 18, 2026
Gene Group: RECEPTOR LIGANDS
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General Information
Name
RECEPTOR LIGANDS
Species
D. melanogaster
Symbol
RLIG
FlyBase ID
FBgg0001105
Date last reviewed
2026-05-26
Number of members
117
Description
Description
Receptor ligands are endogenous polypeptides that bind transmembrane cell surface receptors to elicit a cellular response.
Notes on Group

The RECEPTOR LIGANDS gene group is not an fully comprehensive list of ligands, but a collection of ligand families and genes with GO annotations indicating ligand activity.

Source Material
The RECEPTOR LIGANDS Gene Group has been compiled using the following publication(s): Rojo-Cortés et al., 2026, Guo et al., 2025, Nässel, 2025, Nässel, 2025, Scholz et al., 2023, Li et al., 2022, Boulanger et al., 2021, Mele and Johnson, 2019, Anthoney et al., 2018, Post et al., 2018, Amarnath et al., 2017, Foldi et al., 2017, Lee et al., 2017, Upadhyay et al., 2017, Chakrabarti et al., 2016, Koyama and Mirth, 2016, Lamiable et al., 2016, Lee et al., 2016, Roh et al., 2016, Yoo et al., 2016, Andersen et al., 2015, Reynaud et al., 2015, Jung et al., 2014, Veenstra and Ida, 2014, Yamamoto et al., 2014, Emerson et al., 2013, Jiang et al., 2013, Manning et al., 2013, Muha and Müller, 2013, Andersen et al., 2012, Herr and Basler, 2012, Matsumoto et al., 2012, Osman et al., 2012, Rajan and Perrimon, 2012, Tsuzuki et al., 2012, Ida et al., 2011, Ida et al., 2011, Wright et al., 2011, Kim et al., 2010, Kim et al., 2010, Nässel and Winther, 2010, Veenstra, 2009, Wang and Zhu, 2009, Zlatic et al., 2009, Wegener and Gorbashov, 2008, Zhu et al., 2008, Bates and Whitington, 2007, Yang et al., 2007, Ayoob et al., 2006, Englund et al., 2006, Wu and Brown, 2006, Yazdani and Terman, 2006, Hombria et al., 2005, Itoh and Ornitz, 2004, Hoch and Soriano, 2003, Castellani and Rougon, 2002, Nassel, 2002, Urban et al., 2002, Bahri et al., 2001, Llimargas and Lawrence, 2001, Parker et al., 2001, Fremion et al., 2000, Yu and Kolodkin, 1999, Wolfner et al., 1997, Schnepp et al., 1996, and Hart et al., 1993 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Other related group(s)
Members (117)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
RLIG
RECEPTOR LIGANDS
Secondary FlyBase ID(s)
References (67)