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Citation
Upadhyay, A., Moss-Taylor, L., Kim, M.J., Ghosh, A.C., O'Connor, M.B. (2017). TGF-β Family Signaling in Drosophila.  Cold Spring Harbor Perspect. Biol. 9(9): a022152.
FlyBase ID
FBrf0236482
Publication Type
Review
Abstract

The transforming growth factor β (TGF-β) family signaling pathway is conserved and ubiquitous in animals. In Drosophila, fewer representatives of each signaling component are present compared with vertebrates, simplifying mechanistic study of the pathway. Although there are fewer family members, the TGF-β family pathway still regulates multiple and diverse functions in Drosophila. In this review, we focus our attention on several of the classic and best-studied functions for TGF-β family signaling in regulating Drosophila developmental processes such as embryonic and imaginal disc patterning, but we also describe several recently discovered roles in regulating hormonal, physiological, neuronal, innate immunity, and tissue homeostatic processes.

PubMed ID
PubMed Central ID
PMC5585851 (PMC) (EuropePMC)
Related Publication(s)
Erratum

Erratum: TGF-β Family Signaling in Drosophila.
Upadhyay et al., 2017, Cold Spring Harbor Perspect. Biol. 9(3): a031963 [FBrf0236561]

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cold Spring Harbor Perspect. Biol.
    Title
    Cold Spring Harbor perspectives in biology
    ISBN/ISSN
    1943-0264
    Data From Reference