TGFβ family ligand - concentrated in the foregut - broad expression pattern suggests that signaling could be permissive rather than instructive during stomatogastric nervous system precursor migration - neuromuscular junction glia release Maverick, which likely activates the muscle activin-type receptor Punt to potently modulate Gbb-dependent retrograde signaling and synaptic growth
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
There is only one protein coding transcript and one polypeptide associated with this gene
701, 433 (aa)
mav protein belongs to the TGF-β superfamily but is not easily assigned to either the TGF-β, the BMP or activin subfamilies. It shows the highest sequence similarity with BMP-related ligands from other organisms.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mav using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\mav in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.