FlyBase Allele Report: Dmel\mav[ko]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\mav^ko

General Information

Symbol

Dmel\mav^ko

Species

D. melanogaster

Name

FlyBase ID

FBal0343412

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Hoyer et al., 2018)

Mutagen

gene targeting by homologous recombination

(Hoyer et al., 2018)

(Hoyer et al., 2018)

Progenitor genotype

Associated Insertion(s)

Cytology

Description

The mav coding sequence has been replaced with sequence encoding a w^GMR.PH marker.

(Hoyer et al., 2018)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

4:623,360..625,586 [-]

Comment:

The mav coding sequence ( 4:623360..625586 ) has been replaced with sequence encoding a w^GMR.PH marker.

(Soba, 2019.2.2)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | third instar larval stage

(Hoyer et al., 2018)

abnormal size | third instar larval stage

(Hoyer et al., 2018)

(Hoyer et al., 2018)

(Hoyer et al., 2018)

Phenotype Manifest In

dendritic tree | third instar larval stage

(Hoyer et al., 2018)

larval multidendritic class IV neuron | third instar larval stage

(Hoyer et al., 2018)

Detailed Description

Statement

Reference

mav^ko third instar larval C4da neurons exhibit a less complex dendrite tree (i.e. shorter dendrites with fewer terminals but more isoneuronal dendritic crossings, increased proportion of detached dendrites, and a less radial arrangement), associated with a decreased dendritic growth, as compared to controls.

(Hoyer et al., 2018)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Ret^ko, mav^ko has abnormal neuroanatomy | third instar larval stage phenotype, non-enhanceable by mav^+tBAC

(Hoyer et al., 2018)

Ret^ko, mav^ko has abnormal size | third instar larval stage phenotype, non-enhanceable by mav^+tBAC

(Hoyer et al., 2018)

mav^ko has abnormal neuroanatomy | third instar larval stage phenotype, non-enhanceable by Ret^ko

(Hoyer et al., 2018)

mav^ko has abnormal size | third instar larval stage phenotype, non-enhanceable by Ret^ko

(Hoyer et al., 2018)

Suppressed by

Statement

Reference

Ret^ko, mav^ko has abnormal neuroanatomy | third instar larval stage phenotype, suppressible | partially by Scer\GAL4^ppk.PG/Ret^UAS.Tag:V5

(Hoyer et al., 2018)

Ret^ko, mav^ko has abnormal size | third instar larval stage phenotype, suppressible | partially by Scer\GAL4^ppk.PG/Ret^UAS.Tag:V5

(Hoyer et al., 2018)

NOT suppressed by

Statement

Reference

mav^ko has abnormal neuroanatomy | third instar larval stage phenotype, non-suppressible by Ret^ko

(Hoyer et al., 2018)

mav^ko has abnormal size | third instar larval stage phenotype, non-suppressible by Ret^ko

(Hoyer et al., 2018)

Ret^ko, mav^ko has abnormal neuroanatomy | third instar larval stage phenotype, non-suppressible by mav^+tBAC

(Hoyer et al., 2018)

Ret^ko, mav^ko has abnormal size | third instar larval stage phenotype, non-suppressible by mav^+tBAC

(Hoyer et al., 2018)

Enhancer of

Statement

Reference

mav^ko is an enhancer of abnormal neuroanatomy | third instar larval stage phenotype of Ret^ko

(Hoyer et al., 2018)

mav^ko is an enhancer of abnormal size | third instar larval stage phenotype of Ret^ko

(Hoyer et al., 2018)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

mav^ko has larval multidendritic class IV neuron | third instar larval stage phenotype, non-enhanceable by Ret^ko

(Hoyer et al., 2018)

mav^ko has dendritic tree | third instar larval stage phenotype, non-enhanceable by Ret^ko

(Hoyer et al., 2018)

Ret^ko, mav^ko has larval multidendritic class IV neuron | third instar larval stage phenotype, non-enhanceable by mav^+tBAC

(Hoyer et al., 2018)

Ret^ko, mav^ko has dendritic tree | third instar larval stage phenotype, non-enhanceable by mav^+tBAC

(Hoyer et al., 2018)

Suppressed by

Statement

Reference

Ret^ko, mav^ko has larval multidendritic class IV neuron | third instar larval stage phenotype, suppressible | partially by Scer\GAL4^ppk.PG/Ret^UAS.Tag:V5

(Hoyer et al., 2018)

Ret^ko, mav^ko has dendritic tree | third instar larval stage phenotype, suppressible | partially by Scer\GAL4^ppk.PG/Ret^UAS.Tag:V5

(Hoyer et al., 2018)

NOT suppressed by

Statement

Reference

mav^ko has larval multidendritic class IV neuron | third instar larval stage phenotype, non-suppressible by Ret^ko

(Hoyer et al., 2018)

mav^ko has dendritic tree | third instar larval stage phenotype, non-suppressible by Ret^ko

(Hoyer et al., 2018)

Ret^ko, mav^ko has larval multidendritic class IV neuron | third instar larval stage phenotype, non-suppressible by mav^+tBAC

(Hoyer et al., 2018)

Ret^ko, mav^ko has dendritic tree | third instar larval stage phenotype, non-suppressible by mav^+tBAC

(Hoyer et al., 2018)

Enhancer of

Statement

Reference

mav^ko is an enhancer of larval multidendritic class IV neuron | third instar larval stage phenotype of Ret^ko

(Hoyer et al., 2018)

mav^ko is an enhancer of dendritic tree | third instar larval stage phenotype of Ret^ko

(Hoyer et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

mav^ko is partially rescued by mav^+tBAC

(Hoyer et al., 2018)

mav^ko is partially rescued by mav^{fTRG00891.sfGFP-TVPTBF}

(Hoyer et al., 2018)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

mav^ko

(Soba, 2019.2.2, Hoyer et al., 2018)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections