Glutathione transferases (glutathione S-transferases, GST) catalyze nucleophilic attack by reduced glutathione on non-polar compounds that contain an electrophilic carbon, nitrogen, or sulfur atom. Microsomal GSTs are membrane-associated proteins involved in eicosanoid and glutathione metabolism. (Adapted from
FBrf0202224 and
PMID:15822171.)
