FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene Group: PPPDE DEUBIQUITINASES
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General Information
Name
PPPDE DEUBIQUITINASES
Species
D. melanogaster
Symbol
PPPDE
FlyBase ID
FBgg0001451
Date last reviewed
2020-06-08
Number of members
2
Description
Description
PPPDE deubiquitinases are cysteine isopeptidases related to human PPPDE1 that deubiquitinate Lys 48-linked ubiquitination, thereby stabilizing target proteins. PPPDE deubiquitinases are included within MEROPS family C97. (Adapted from PMID:28483520.)
Notes on Group
Source Material
The PPPDE DEUBIQUITINASES Gene Group has been compiled using the following publication(s): Rawlings and Barrett, 1996- .
Key Gene Ontology (GO) terms
Molecular Function
cysteine-type deubiquitinase activity
Biological Process
protein deubiquitination
Cellular Component
Enzymatic activity
Enzyme name (EC)
ubiquitinyl hydrolase 1 (3.4.19.12)
Related Gene Groups
Parent group(s)
CYSTEINE-TYPE DEUBIQUITINASES
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)

[MEROPS Family C97](https://www.ebi.ac.uk/merops/cgi-bin/famsum?family=c97)

Synonyms and Secondary IDs
Synonym(s)
PPPDE
PPPDE DEUBIQUITINASES
Secondary FlyBase ID(s)
References (3)