FB2026_02 , released June 18, 2026
Gene Group: CYSTEINE-TYPE DEUBIQUITINASES
Open Close
General Information
Name
CYSTEINE-TYPE DEUBIQUITINASES
Species
D. melanogaster
Symbol
CYS-DUB
FlyBase ID
FBgg0001395
Date last reviewed
2020-05-26
Number of members
36
Description
Description
Deubiquitinases (DUBs) catalyze the proteolytic removal of ubiquitin from ubiquitin chains and ubiquinated proteins. Most are cysteine peptidases, which can be classified into several subfamilies. (Adapted from PMID:19626045 and PMID:19489724.)
Notes on Group
Source Material
The CYSTEINE-TYPE DEUBIQUITINASES Gene Group has been compiled using the following publication(s): Erven et al., 2022, Páhi et al., 2022, Badmos et al., 2021, Engel et al., 2014, Clague et al., 2013, Tsou et al., 2012, Zhang et al., 2012, and Rawlings and Barrett, 1996- .
Key Gene Ontology (GO) terms
Molecular Function
cysteine-type deubiquitinase activity
Biological Process
protein deubiquitination
Cellular Component
Enzymatic activity
Enzyme name (EC)
ubiquitinyl hydrolase 1 (3.4.19.12)
Related Gene Groups
Parent group(s)
DEUBIQUITINASES
UBIQUITIN-LIKE PROTEIN CYSTEINE PROTEASES
Component group(s)
CYSTEINE-TYPE OTU DEUBIQUITINASES
JOSEPHIN DEUBIQUITINASES
MINDY DEUBIQUITINASES
PPPDE DEUBIQUITINASES
UCH DEUBIQUITINASES
USP DEUBIQUITINASES
VIRAL TEGUMENT-LIKE DEUBIQUITINASES
Members (36)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
CYS-DUB
CYSTEINE-TYPE DEUBIQUITINASES
Secondary FlyBase ID(s)
References (10)