FB2026_03 , released September 17, 2026
Gene Group: DEUBIQUITINASES
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General Information
Name
DEUBIQUITINASES
Species
D. melanogaster
Symbol
DUB
FlyBase ID
FBgg0000165
Date last reviewed
2014-02-24
Number of members
44
Description
Description
Deubiquitinases (DUBs) catalyze the proteolytic removal of ubiquitin from ubiquitin chains and ubiquitinated proteins. Most are cysteine peptidases, though the JAMM domain-containing deubiquitinases are metallopeptidases. (Adapted from PMID:19626045 and PMID:19489724.)
Notes on Group
Source Material
The DEUBIQUITINASES Gene Group has been compiled using the following publication(s): Erven et al., 2022, Páhi et al., 2022, Badmos et al., 2021, Louis et al., 2015, Engel et al., 2014, Clague et al., 2013, Tsou et al., 2012, Zhang et al., 2012, and Rawlings and Barrett, 1996- .
Key Gene Ontology (GO) terms
Molecular Function
deubiquitinase activity
Biological Process
protein deubiquitination
Cellular Component
Related Gene Groups
Parent group(s)
UBIQUITIN-LIKE PROTEIN PEPTIDASES
Component group(s)
CYSTEINE-TYPE DEUBIQUITINASES
JAMM DEUBIQUITINASES
SERINE-TYPE OTU DEUBIQUITINASES
Members (44)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
DUB
DEUBIQUITINASES
Deubiquitylase
Deubiquitinating Enzymes
De-ubiquitinases
Deubiquitinating peptidases
Deubiquitinating isopeptidases
Ubiquitin proteases
Ubiquitin hydrolases
Ubiquitin isopeptidases
DUBs
UPS
Secondary FlyBase ID(s)
References (11)