FB2026_02 , released June 18, 2026
Gene Group: CYTOCHROME P450 - CYP4 CLAN
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General Information
Name
CYTOCHROME P450 - CYP4 CLAN
Species
D. melanogaster
Symbol
CYP450-CYP4
FlyBase ID
FBgg0001696
Date last reviewed
2021-03-11
Number of members
32
Description
Description
Cytochrome P450, or CYP genes, constitute one of the largest families of genes, with representatives in virtually all living organisms. P450 enzymes are heme-thiolate proteins best known for their monooxygenase role, catalyzing the transfer of one atom of molecular oxygen to a substrate and reducing the other to water. The CYP4 clan includes D. melanogaster CYP4, 311-313, 316 and 318 family genes. Few CYP4 enzymes have been characterized, though some CYP4 genes are inducible by xenobiotics. (Adapted from FBrf0248421.)
Notes on Group
Source Material
The CYTOCHROME P450 - CYP4 CLAN Gene Group has been compiled using the following publication(s): Dermauw et al., 2020, Feyereisen, 2012, Feyereisen, 2006, and Tijet et al., 2001 .
Key Gene Ontology (GO) terms
Molecular Function
monooxygenase activity
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
CYTOCHROME P450
Members (32)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
CYP450-CYP4
CYP4
CYTOCHROME P450 - CYP4 CLAN
Secondary FlyBase ID(s)
References (5)