FB2026_03 , released September 17, 2026
Gene Group: GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASES
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General Information
Name
GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASES
Species
D. melanogaster
Symbol
GILT
FlyBase ID
FBgg0001734
Date last reviewed
2021-04-23
Number of members
5
Description
Description
Gamma-interferon-inducible lysosomal thiol reductases catalyze disulfide bond reduction of endocytosed proteins within the acidic environment of lysosomes. They are involved in the immune response to bacterial challenge in various organisms. (Adapted from FBrf0224365.)
Notes on Group
Source Material
The GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASES Gene Group has been compiled using the following publication(s): Kongton et al., 2014 .
Key Gene Ontology (GO) terms
Molecular Function
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
Biological Process
Cellular Component
Enzymatic activity
Enzyme name (EC)
1.8.4.-
Related Gene Groups
Parent group(s)
SULFUR OXIDOREDUCTASES, DISULFIDE AS ACCEPTOR
Members (5)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
GILT
GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASES
Secondary FlyBase ID(s)
References (3)