FB2026_03 , released September 17, 2026
Complex: miRNA-INDUCED SILENCING COMPLEX
Open Close
General Information
Name
miRNA-INDUCED SILENCING COMPLEX
Species
D. melanogaster
Symbol
miRISC
FlyBase ID
FBgg0001801
Date last reviewed
2022-11-02
Number of members
2
Description
Description
The miRNA RNA-induced silencing complex (miRISC) mediates post-transcriptional repression of gene expression by incorporating mature miRNA and down-regulating the expression of the target mRNA via repression of translation or mRNA degradation. (Adapted from FBrf0247552 and FBrf0194513.)
Notes on Group

The miRNA-INDUCED SILENCING COMPLEX was sourced from Complex Portal, curated by EMBL-EBI.

Source Material
The miRNA-INDUCED SILENCING COMPLEX Gene Group has been compiled using the following publication(s): Behm-Ansmant et al., 2006 .
Key Gene Ontology (GO) terms
Molecular Function
Cellular Component
Related Gene Groups
Protein Complex group(s)
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
miRISC
miRNA-INDUCED SILENCING COMPLEX
Secondary FlyBase ID(s)
References (2)