Gene Group: P-TYPE ATPASE TRANSPORTERS

General Information

Name

P-TYPE ATPASE TRANSPORTERS

Species

D. melanogaster

Symbol

P-TMT

FlyBase ID

FBgg0001895

Date last reviewed

2023-12-12

Number of members

Description

P-type ATPases are primary active transmembrane transporters that transport charged substrates like ions and phospholipids against a concentration gradient. P-type ATPases use ATP to auto-phosphorylate during the catalytic cycle at an invariant aspartate residue, resulting in conversion between "inward-facing" and "outward-facing" conformations that facilitate substrate transport. (Adapted from PMID:37838176.)

Notes on Group

Source Material

The P-TYPE ATPASE TRANSPORTERS Gene Group has been compiled using the following publication(s): Shiomi et al., 2021, Tabuchi et al., 2018, Roy et al., 2013, Ma et al., 2012, Sellami et al., 2012, Desai and Lnenicka, 2011, Tanaka et al., 2011, Bahadorani et al., 2010, Baumann et al., 2010, Burke et al., 2008, Lnenicka et al., 2006, Masly et al., 2006, Norgate et al., 2006, Southall et al., 2006, Roos et al., 2005, Southon et al., 2004, Okamura et al., 2003, Cronin et al., 2002, Xu et al., 1999, Emery et al., 1998, and Magyar and Varadi, 1990 .

Key Gene Ontology (GO) terms

Molecular Function

P-type transmembrane transporter activity

Biological Process

transmembrane transport

Cellular Component

membrane

Related Gene Groups

Parent group(s)

P-P-BOND-HYDROLYSIS-DRIVEN TRANSPORTERS

Component group(s)

COPPER TRANSPORTING P-ATPASES