FB2026_03 , released September 17, 2026
Gene Group: CLASSICAL PROTEIN KINASE C SUBFAMILY
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General Information
Name
CLASSICAL PROTEIN KINASE C SUBFAMILY
Species
D. melanogaster
Symbol
CPKC
FlyBase ID
FBgg0001991
Date last reviewed
2025-01-07
Number of members
2
Description
Description
The Protein Kinase C (PKC) family are serine/threonine kinases. PKCs are regulated by auto-inhibition through a pseudosubstrate site located in the regulatory domain. Members of the classical PKC (cPKC) subfamily require diacylglycerol and Ca[2+] for activation. (Adapted from PMID:20094051 and FBrf0152086).
Notes on Group
Source Material
The CLASSICAL PROTEIN KINASE C SUBFAMILY Gene Group has been compiled using the following publication(s): Sopko et al., 2014, Manning et al., 2002, Shieh et al., 2002, and Morrison et al., 2000 .
Key Gene Ontology (GO) terms
Molecular Function
calcium,diacylglycerol-dependent serine/threonine kinase activity
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
PROTEIN KINASE C FAMILY
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
CPKC
CLASSICAL PROTEIN KINASE C SUBFAMILY
NOVEL PROTEIN KINASE C SUBFAMILY
Secondary FlyBase ID(s)
References (5)