TRAPP (TRAnsport Protein Particle) tethering complexes are involved in vesicle trafficking in the secretory pathway. There are two TRAPP complexes in metazoans, TRAPPII and TRAPPIII. A minimal shared core complex subunits, TRAPPC1, TRAPPC3 and TRAPPC4, is sufficient for GEF activity in vitro. (Adapted from
FBrf0238107 and
PMID:36477798.)