Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Su(var) using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\Su(var) in JBrowse3-41.3
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
One of a series of dominant suppressors of variegation, mostly selected on the basis of their ability to suppress the mottling of In(1)wm4; where they have been tested, these mutations suppress variegated type position effects involving other loci as well. Two groups have performed extensive mutagenesis experiments, but there has apparently been no exchange of material nor any attempt to determine allelic relationships between the two samples of mutants. The Canadian group has designated its mutants as a Su(var)200 series for second-chromosome mutations and a Su(var)300 series for third-chromosome mutations. The German group uses Su-var(3)1, etc. to designate a series of suppressors on the third chromosome; Lindsley and Zimm (1992) reconciled these terminologies but keep them separate by altering the second nomenclature to Su(var)3-1, etc. Despite the fact that some mutants from the two groups map to virtually identical positions, Lindsley and Zimm (1992) listed them separately until appropriate complementation tests are performed. Most of these suppressors appear to be loss of function mutations and are frequently associated with deficiencies; in addition variegation suppression is often produced by heterozygous deficiencies for their loci. Of these, several have been shown to enhance variegation when duplicated (Tartof, Bishop, Jones, Hobbs and Locke, 1989).