Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Tango10 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Tango10 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Tango10 CG1841
dsRNA directed against this gene has been used in a screen for genes required for constitutive protein secretion.
dsRNA directed against Tango10 inhibits protein secretion in S2 cells, but has no apparent effect on Golgi organisation.
dsRNA has been made from templates generated with primers directed against this gene. RNAi of Tango10 causes a reduction in the arborization of ddaD and ddaE neurons. There is a severe reduction in primary branch outgrowth, lateral branching and lateral branch length. Additionally, there is also inappropriate dendritic routing of ddaE neurons. Additionally, RNAi causes defects in muscle and defects in dendrite morphogenesis.