FlyBase Gene Report: Dmel\Tep5Ψ

General Information

Symbol

Dmel\Tep5Ψ

Species

D. melanogaster

Name

Thioester-containing protein 5 pseudogene

Annotation Symbol

CR13079

Feature Type

pseudogene

FlyBase ID

FBgn0264845

Gene Model Status

Current

Stock Availability

10 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Interactive Fly

Also Known As

Tep5, TepV, dTEPV

Key Links

Genomic Location

Cytogenetic map

37F1-37F1

Sequence location

2L:19,558,916..19,563,049 [+]

Recombination map

2-54

RefSeq locus

NT_033779 REGION:19558916..19563049

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (0 terms)

Molecular Function (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Tep5Ψ for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Pseudogene similar to Tep4; proximate; corresponds to Tep5 (TepV) in related species.

Gene model reviewed during 5.44

Gene model reviewed during 6.28

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Tep5Ψ-RC

FBtr0475187

3921

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Tep5Ψ using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

NA

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Tep5Ψ in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Tep5Ψ

View exonic expression by tissue for Dmel\Tep5Ψ

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

35250/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0264845

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0032808

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0264845

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 6 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 4 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Tep5Ψ

Transgenic constructs containing regulatory region of Tep5Ψ

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(2L)Exel8041

(Ryder, 2004.4.26)

Inferred from location ( 5 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (10)

Hsap\A2M

1 of 14

Yes

Hsap\A2ML1

1 of 14

Yes

Hsap\C4A

1 of 14

Yes

Hsap\C4B_2

1 of 14

Yes

Hsap\C4B

1 of 14

Yes

Hsap\C5

1 of 14

Yes

Hsap\CD109

1 of 14

Yes

Hsap\CPAMD8

1 of 14

Yes

Hsap\LOC110384692

1 of 14

Yes

Hsap\PZP

1 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (11)

Rnor\A2ml1

1 of 14

Yes

Rnor\A2m

1 of 14

Yes

Rnor\C4a

1 of 14

Yes

Rnor\C4b

1 of 14

Yes

Rnor\C5

1 of 14

Yes

Rnor\Cd109

1 of 14

Yes

Rnor\Cpamd8

1 of 14

Yes

Rnor\LOC297568

1 of 14

Yes

Rnor\Mug1

1 of 14

Yes

Rnor\Mug2

1 of 14

Yes

Rnor\Pzp

1 of 14

Yes

Mus musculus (laboratory mouse) (8)

Mmus\A2ml1

1 of 14

Yes

Mmus\A2m

1 of 14

Yes

Mmus\C4a

1 of 14

Yes

Mmus\C4b

1 of 14

Yes

Mmus\Cd109

1 of 14

Yes

Mmus\Mug1

1 of 14

Yes

Mmus\Mug2

1 of 14

Yes

Mmus\Pzp

1 of 14

Yes

Xenopus tropicalis (Western clawed frog) (31)

Xtro\a2ml1

1 of 13

Yes

Xtro\a2m

1 of 13

Yes

Xtro\c4a

1 of 13

Yes

Xtro\c5

1 of 13

Yes

Xtro\cd109

1 of 13

Yes

Xtro\cpamd8

1 of 13

Yes

Xtro\LOC619594

1 of 13

Yes

Xtro\LOC100170611

1 of 13

Yes

Xtro\LOC100487426

1 of 13

Yes

Xtro\LOC100487578

1 of 13

Yes

Xtro\LOC100487580

1 of 13

Yes

Xtro\LOC100487726

1 of 13

Yes

Xtro\LOC100487748

1 of 13

Yes

Xtro\LOC100488897

1 of 13

Yes

Xtro\LOC100489060

1 of 13

Yes

Xtro\LOC100491968

1 of 13

Yes

Xtro\LOC100492134

1 of 13

Yes

Xtro\LOC100494685

1 of 13

Yes

Xtro\LOC100495827

1 of 13

Yes

Xtro\LOC101730404

1 of 13

Yes

Xtro\LOC101730963

1 of 13

Yes

Xtro\LOC101731171

1 of 13

Yes

Xtro\LOC101732535

1 of 13

Yes

Xtro\LOC101734901

1 of 13

Yes

Xtro\LOC105945599

1 of 13

Yes

Xtro\LOC108644460

1 of 13

Yes

Xtro\LOC108645185

1 of 13

Yes

Xtro\LOC108646250

1 of 13

Yes

Xtro\LOC108647609

1 of 13

Yes

Xtro\ovos2

1 of 13

Yes

Xtro\pzp

1 of 13

Yes

Danio rerio (Zebrafish) (22)

Drer\a2ml2

1 of 14

Yes

Drer\a2ml

1 of 14

Yes

Drer\c4b

1 of 14

Yes

Drer\c4

1 of 14

Yes

Drer\c5

1 of 14

Yes

Drer\cd109

1 of 14

Yes

Drer\cpamd8

1 of 14

Yes

Drer\LOC407643

1 of 14

Yes

Drer\LOC569025

1 of 14

Yes

Drer\LOC100006895

1 of 14

Yes

Drer\LOC101886227

1 of 14

Yes

Drer\LOC103909927

1 of 14

Yes

Drer\LOC108179231

1 of 14

Yes

Drer\si:ch211-212c13.10

1 of 14

Yes

Drer\si:dkey-46g23.2

1 of 14

Yes

Drer\si:dkey-46g23.5

1 of 14

Yes

Drer\si:dkey-105h12.2

1 of 14

Yes

Drer\zgc:165453

1 of 14

Yes

Drer\zgc:165518

1 of 14

Yes

Drer\zgc:171426

1 of 14

Yes

Drer\zgc:171445

1 of 14

Yes

Drer\zgc:171446

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

Cele\tep-1

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (13)

Agam\TEP1

1 of 12

Yes

Agam\TEP2

1 of 12

Yes

Agam\TEP3

1 of 12

Yes

Agam\TEP4

1 of 12

Yes

Agam\TEP6

1 of 12

Yes

Agam\TEP8

1 of 12

Yes

Agam\TEP9

1 of 12

Yes

Agam\TEP10

1 of 12

Yes

Agam\TEP11

1 of 12

Yes

Agam\TEP13

1 of 12

Yes

Agam\TEP14

1 of 12

Yes

Agam\TEP15

1 of 12

Yes

Agam\TEP19

1 of 12

Yes

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Tep5Ψ. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (5)

Mcr

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0264845

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

nuclear_gene

pseudogene

(FlyBase Genome Annotators, 2019)

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-54

Cytogenetic map

37F1-37F1

Sequence location

2L:19,558,916..19,563,049 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

37F1-37F1

Left limit from (method unavailable) (FBrf0126883) Right limit from (method unavailable) (FBrf0126883); Limits computationally determined from genome sequence between P{EP}EP623&P{PZ}spi⁰¹⁰⁶⁸ and P{lacW}l(2)k10239^k10239

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

37F1-37F2

(Lagueux, 2000.3.15)

Experimentally Determined Recombination Data

Location

2-54

(FlyBase, 2016)

2-53.7

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (10)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

61328

y¹ v¹; P{TRiP.HMJ23163}attP40

41448

y¹ w^*; Mi{MIC}Tep5Ψ^MI06511

13790

y¹ w^67c23; P{SUPor-P}Tep5Ψ^KG03507

97705

y¹ w^*; TI{CRIMIC.TG4.1}Tep5Ψ^{CR02961-TG4.1}/SM6a

NIG-Fly

HMJ23163

y¹ v¹; P{TRiP.HMJ23163}attP40/CyO

M2L-3447

y¹ w¹¹¹⁸; Tep5Ψ^SK13 P{neoFRT}40A/CyO-Tb

M2L-3448

y¹ w¹¹¹⁸; Tep5Ψ^SK14 P{neoFRT}40A/CyO-Tb

2LG-1820

y² VhaAC39-1^cho-1 v¹; P{U6-Tep5Ψ.NIG.sgRNA.1}attP40/CyO

2LG-3326

y² VhaAC39-1^cho-1 v¹; P{U6-Tep5Ψ.NIG.sgRNA.2}attP40/CyO

VDRC

v31866

P{GD7663}v31866

Genomic Clones (12)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (1)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

CR13079 reclassified as a pseudogene gene in r6.28.

(FlyBase Genome Annotators, 2019)

Relationship to Other Genes

Source for database merge of

Source for merge of: CG13079 CG13080

(FlyBase Genome Annotators, 2002-2003)

Source for merge of: TepV CG13079

(Bou Aoun et al., 2011)

Additional comments

Annotations CG13079 and CG13080 merged as CG13080 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (13)

Reported As

Symbol Synonym

CG13079

(National Institute of Genetics Fly Stocks, 2022-, Bou Aoun et al., 2011, Perkins et al., 2009)

CG13080

CR13079

(FlyBase Genome Annotators, 2019)

TEP5mel

(Bou Aoun et al., 2011)

Tep5

(Shokal and Eleftherianos, 2017, Péan and Dionne, 2014, Bou Aoun et al., 2008, Lagueux et al., 2000)

Tep5Psi

(Gene Disruption Project members, 2018-)

Tep5Ψ

TepV

(Christophides et al., 2002)

dTEPV

(Lagueux, 2000.3.15, Lagueux et al., 2000)

Name Synonyms

TEP

(Erturk-Hasdemir and Silverman, 2005)

Thioester-containing protein 5

Thioester-containing protein 5 pseudogene

Thiolester containing protein V

(Lagueux et al., 2000)

Secondary FlyBase IDs

FBgn0032808
FBgn0032807
FBgn0041179

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 11 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

35250

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

Other crossreferences

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

35250/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0264845

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0264845

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CR13079

MARRVEL_MODEL - MARRVEL (model organism gene)

35250

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0264845

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0032808

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0264845

References (31)

The following external sites may use different assemblies or annotations than FlyBase.

NA

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