FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Human Disease Model Report: high-fat diet, insulin pathway effects
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General Information
Name
high-fat diet, insulin pathway effects
FlyBase ID
FBhh0000530
Disease Ontology Term
Parent Disease
OMIM
Overview

Adult flies fed a high-fat diet develop a number of phenotypes associated with type-2 diabetes, including elevated triglyceride and circulating glucose levels, and insulin resistance. See also the human disease model report for 'high-fat diet, obesity' (FBhh0000495).

[updated Apr. 2017 by FlyBase; FBrf0222196]

Disease Summary Information
Disease Summary: high-fat diet, insulin pathway effects
OMIM report
Human gene(s) implicated
Symptoms and phenotype
Genetics
Cellular phenotype and pathology
Molecular information
External links
    Disease synonyms
    diabesity
    HFD, insulin pathway effects
    lipotoxicity
    Ortholog Information
    Human gene(s) in FlyBase
      Other mammalian ortholog(s) used
        D. melanogaster Gene Information (0)
        Other Genes Used: Viral, Bacterial, Synthetic (0)
          Summary of Physical Interactions (0 groups)
          Alleles Reported to Model Human Disease (Disease Ontology) (0 alleles)
          Alleles Representing Disease-Implicated Variants
          Genetic Tools, Stocks and Reagents
          Sources of Stocks
          Contact lab of origin for a reagent not available from a public stock center.
          Bloomington Stock Center Disease Page
          Related mammalian, viral, bacterial, or synthetic transgenes
          Allele
          Transgene
          Publicly Available Stocks
          Selected Drosophila transgenes
          Allele
          Transgene
          Publicly Available Stocks
          RNAi constructs available
          Allele
          Transgene
          Publicly Available Stocks
          Selected Drosophila classical alleles
          Allele
          Allele class
          Mutagen
          Publicly Available Stocks
          References (34)