FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Human Disease Model Report: hematologic cancer (fly models overview)
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General Information
Name
hematologic cancer (fly models overview)
FlyBase ID
FBhh0000803
Disease Ontology Term
Parent Disease
OMIM
Overview

This report includes links to reviews and general information on the Drosophila hematopoietic system and fly models of hematologic cancer. The hematopoietic system in Drosophila is composed of hemocytes with functions similar to human myeloid cells; like all invertebrates, Drosophila lack cells of the lymphoid lineage.

References describing biology of this Drosophila system, methods and assays: Crozatier and Vincent, 2011 (FBrf0214023); Evans, et al., 2014 (FBrf0225270); Letourneau, et al., 2016 (FBrf0234024); El Chamy, et al., 2017 (FBrf0234561); Banerjee et al., 2019 (FBrf0241407); Outa et al., 2020 (FBrf0246272).

For a listing of Drosophila models of hematologic cancer see the "Related Diseases" section, below, or go to the FlyBase Human Disease Model Report Index (http://flybase.org/lists/FBhh/).

[updated Aug. 2020 by FlyBase; FBrf0222196]

Disease Summary Information
Disease Summary: hematologic cancer (fly models overview)
OMIM report
Human gene(s) implicated
Symptoms and phenotype

Hematologic cancers begin in blood-forming tissue, such as the bone marrow or the cells of the immune system, and include leukemia, lymphoma, and multiple myeloma.

(FlyBase Curators, 2013-)
Genetics
Cellular phenotype and pathology
Molecular information
External links
    Disease synonyms
    haematopoietic cancer
    haematopoietic malignancy
    hematologic cancer
    hematologic neoplasm
    hematopoietic cancer
    hematopoietic malignancy
    Search term: cancer of the blood
    Search term: leukemia
    Ortholog Information
    Human gene(s) in FlyBase
      Other mammalian ortholog(s) used
        D. melanogaster Gene Information (0)
        Other Genes Used: Viral, Bacterial, Synthetic (0)
          Summary of Physical Interactions (0 groups)
          Alleles Reported to Model Human Disease (Disease Ontology) (0 alleles)
          Alleles Representing Disease-Implicated Variants
          Genetic Tools, Stocks and Reagents
          Sources of Stocks
          Contact lab of origin for a reagent not available from a public stock center.
          Bloomington Stock Center Disease Page
          Related mammalian, viral, bacterial, or synthetic transgenes
          Allele
          Transgene
          Publicly Available Stocks
          Selected Drosophila transgenes
          Allele
          Transgene
          Publicly Available Stocks
          RNAi constructs available
          Allele
          Transgene
          Publicly Available Stocks
          Selected Drosophila classical alleles
          Allele
          Allele class
          Mutagen
          Publicly Available Stocks
          References (8)