FB2026_02 , released June 18, 2026
Human Disease Model Report: cancer, general (fly models overview)
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General Information
Name
cancer, general (fly models overview)
FlyBase ID
FBhh0000782
Disease Ontology Term
Parent Disease
OMIM
Overview

This report includes general reviews of cancer models in Drosophila; see the References section. Reviews for specific categories of cancer can be found in the appropriate human disease model reports; see reports listed in 'Related Diseases', below. The complete list of Drosophila models of cancer is extensive; see the FlyBase Human Disease Model Report Index (http://flybase.org/lists/FBhh/).

Drosophila genetic methods useful in the context of cancer models are reviewed in Villegas et al., 2019 (FBrf0243409). Mosaic analysis is a technique used frequently in fly models of cancer; see also Germani, et al., 2018 (FBrf0237959) for a review of these methods. General methods including the GAL4/UAS system, imaging, and drug screening are described in Cagan et al., 2019 (FBrf0244362). Use of Drosophila models and methods for assessment of large cancer datasets is reviewed in Bangi, 2020 (FBrf0245764).

[updated Jan. 2021 by FlyBase; FBrf0222196]

Disease Summary Information
Disease Summary: cancer, general (fly models overview)
OMIM report
Human gene(s) implicated
Symptoms and phenotype
Genetics
Cellular phenotype and pathology
Molecular information
External links
Disease synonyms
cancer, general
malignancy
malignant neoplasm
tumor
tumour
Ortholog Information
Human gene(s) in FlyBase
    Other mammalian ortholog(s) used
      D. melanogaster Gene Information (0)
      Other Genes Used: Viral, Bacterial, Synthetic (0)
        Summary of Physical Interactions (0 groups)
        Alleles Reported to Model Human Disease (Disease Ontology) (0 alleles)
        Alleles Representing Disease-Implicated Variants
        Genetic Tools, Stocks and Reagents
        Sources of Stocks
        Contact lab of origin for a reagent not available from a public stock center.
        Bloomington Stock Center Disease Page
        Related mammalian, viral, bacterial, or synthetic transgenes
        Allele
        Transgene
        Publicly Available Stocks
        Selected Drosophila transgenes
        Allele
        Transgene
        Publicly Available Stocks
        RNAi constructs available
        Allele
        Transgene
        Publicly Available Stocks
        Selected Drosophila classical alleles
        Allele
        Allele class
        Mutagen
        Publicly Available Stocks
        References (56)