FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
tacc, msps
FlyBase ID
FBig0000088524
Interaction Network
Interactions Browser links
tacc network
msps network
Reported Interactions
FBrf0137062-1.PD.MS
Reference
Lee et al., 2001
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tacc 

D-TACC

bait

MBP tag

msps 

Msps

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from wild-type embryonic extract.

(Lee et al., 2001)
FBrf0137062-2.PD.WB
Reference
Lee et al., 2001
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tacc 

D-TACC

bait

MBP tag

msps 

Msps

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from wild-type embryonic extract.

(Lee et al., 2001)
FBrf0137062-3.coIP.WB
Reference
Lee et al., 2001
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tacc 

D-TACC

bait
msps 

Msps

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Lee et al., 2001)
FBrf0137062-4.coIP.WB
Reference
Lee et al., 2001
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
msps 

Msps

bait
tacc 

D-TACC

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Lee et al., 2001)
FBrf0187814-1.coIP.WB
Reference
Barros et al., 2005
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tacc 

D-TACC

bait

GFP tag

msps 

Msps

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

The tacc S863L mutation does not affect its interaction with msps.

(Barros et al., 2005)

Source was embryos of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Barros et al., 2005)
FBrf0218395-7809.DPiM
Reference
Guruharsha et al., 2011
Description
physical association
Assay
Collection
DPiM-2
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tacc 
unspecified role
tacc 
unspecified role
tacc 
unspecified role
msps 
unspecified role
msps 
unspecified role
msps 
unspecified role
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

HGScore = 98.67789

FBrf0245673-1.coIP.WB
Reference
Tang et al., 2020
Description
physical association
Assay
Collection
Source/Stage
brain / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
msps 

Msps

bait

GFP tag

tacc 

TACC

prey

Venus tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult brains of wildtype or transgenic fly line; bait produced from tagged transgenic construct or endogenous gene; prey produced from transgenic construct or endogenous gene.

(Tang et al., 2020)
FBrf0245673-2.coIP.WB
Reference
Tang et al., 2020
Description
physical association
Assay
Collection
Source/Stage
brain / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tacc 

TACC

bait

Venus tag

msps 

Msps

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult brains of wildtype or transgenic fly line; bait produced from tagged transgenic construct or endogenous gene; prey produced from transgenic construct or endogenous gene.

(Tang et al., 2020)
FBrf0245673-3.coIP.WB
Reference
Tang et al., 2020
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
msps 

Msps

bait

Myc tag

msps 
tacc 

TACC

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
msps 
C-terminal domain
sufficient binding region
aa 1428-2042

coordinates relative to msps-PC

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Tang et al., 2020)
FBrf0245673-4.coIP.WB
Reference
Tang et al., 2020
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
tacc 

TACC

bait

FLAG tag

msps 

Msps

prey

Myc tag

msps 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
msps 
C-terminal domain
sufficient binding region
aa 1428-2042

coordinates relative to msps-PC

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Tang et al., 2020)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (4)