FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Cul3, Nedd8
FlyBase ID
FBig0000095637
Interaction Network
Interactions Browser links
Cul3 network
Nedd8 network
Reported Interactions
FBrf0205968-4.coIP.WB
Reference
Chan et al., 2008
Description
physical association
Assay
Collection
Source/Stage
organism / larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Cul3 

Cul3

bait
Nedd8 

Nedd8

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Bait endogenous to larval extract.

(Chan et al., 2008)

Prey derived from a transgenic line carrying Myc-tagged mature Nedd8, P{UAS-myc-mNedd8}, that does not require Den1 processing.

(Chan et al., 2008)

Cul-3 is neddylated (covalent Nedd8 modification).

(Chan et al., 2008)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)