FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
eIF4E4, Thor
FlyBase ID
FBig0000095725
Interaction Network
Interactions Browser links
eIF4E4 network
Thor network
Reported Interactions
FBrf0184136-10.Y2H
Reference
Hernandez et al., 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
eIF4E4 

4E4

bait

fused to GAL4 DNA-binding domain

Thor 

4EBP

prey

fused to GAL4 activation domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Hernandez et al., 2005)

Two-hybrid system: yeast GAL4-BD/GAL4-AD

(Hernandez et al., 2005)
FBrf0219080-3.Y2H
Reference
Hernandez et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Thor 

4E-BP

bait

fused to GAL4 DNA-binding domain

eIF4E4 

eIF4E-4

prey

fused to GAL4 activation domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Thor interacts with eIF-4E, eIF4E-4 and eIF4E-5, but not with eIF4E-3, in the yeast two-hybrid system.

(Hernandez et al., 2012)

Two-hybrid system: yeast GAL4-BD/GAL4-AD.

(Hernandez et al., 2012)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)