FB2026_03 , released September 17, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Vamp7, Syx17
FlyBase ID
FBig0000096789
Interaction Network
Interactions Browser links
Vamp7 network
Syx17 network
Reported Interactions
FBrf0218395-2514.DPiM
Reference
Guruharsha et al., 2011
Description
physical association
Assay
Collection
DPiM-2
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Vamp7 
unspecified role
Vamp7 
unspecified role
Vamp7 
unspecified role
Syx17 
unspecified role
Syx17 
unspecified role
Syx17 
unspecified role
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

HGScore = 104.52376

FBrf0221516-2.coIP.WB
Reference
Takáts et al., 2013
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Syx17 

Syx17

bait

FLAG tag

Vamp7 

VAMP7

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Takáts et al., 2013)

The interaction of Syx17 with Vamp7 is facilitated by usnp.

(Takáts et al., 2013)
FBrf0224660-6.coIP.WB
Reference
Takáts et al., 2014
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Syx17 

Syx17

bait

FLAG tag

Vamp7 

VAMP7

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Takáts et al., 2014)
FBrf0238842-3.coIP.WB
Reference
Takáts et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Syx17 

Syx17

bait

FLAG tag

Vamp7 

Vamp7

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

The Syx17-Vamp7 interaction was detected in S2 cells when Snap29 and Ykt6 were also expressed. Requirement of Ykt6 or Snap29 coexpression for the Syx17-Vamp7 interaction was not shown.

(Takáts et al., 2018)

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Takáts et al., 2018)
FBrf0238842-5.PD.MW
Reference
Takáts et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Syx17 

Syx17

bait

GST tag

Syx17 
Vamp7 

Vamp7

prey

MBP tag

Vamp7 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Syx17 
SNARE domain
sufficient binding region
unspecified
Vamp7 
SNARE domain
sufficient binding region
unspecified
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Takáts et al., 2018)
FBrf0254939-6.coIP.WB
Reference
Xu et al., 2022
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Vamp7 

Vamp7

bait

V5 tag

Syx17 

Syx17

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Xu et al., 2022)

Vamp7 interaction with Syx17 reduced with Miga RNAi.

(Xu et al., 2022)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (5)