FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
dbo, Cul3
FlyBase ID
FBig0000096911
Interaction Network
Interactions Browser links
dbo network
Cul3 network
Reported Interactions
FBrf0221234-1.coIP.WB
Reference
Strutt et al., 2013
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
dbo 

Dbo

bait

Myc tag

dbo 
dbo 
dbo 
Cul3 

Cul3

prey

Venus tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
dbo 
BTB domain
necessary binding region
aa 72-169
dbo 
BACK domain
necessary binding region
aa 174-276
dbo 
Kelch repeats
necessary binding region
aa 323-623

very weak binding when this domain is deleted

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Strutt et al., 2013)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)