FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000097719
Interaction Network
Interactions Browser links
dlp network
apolpp network
Reported Interactions
FBrf0202296-2.CS.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

ApoLII

neutral component

ApoLII

neutral component

ApoLII

neutral component
dlp 

Dally-like

neutral component

GFP tag

dlp 
dlp 

Dally-like

neutral component

GFP tag

dlp 

Dally-like

neutral component

GFP tag

dlp 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
dlp 
C-terminal region
mutation decreasing interaction
aa 743

R743STOP, removes lipid attachment site

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

An S120 extract, in which plasma membrane and internal membrane compartments were removed by centrifugation, was subjected to Optiprep density gradient fractionation.

The association of dlp with Rfabg is mediated, in part, by its GPI lipid anchor.

Source was larvae of transgenic fly line; proteins produced from endogenous gene or from tagged transgenic construct.

FBrf0202296-5.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
dlp 

Dally-like

bait

CFP tag

dlp 

ApoLII

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
dlp 
N-terminal region
sufficient binding region
aa 1-742

lacks GPI lipid attachment site

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larvae of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

Weak binding. Test for interaction using a full length dlp construct was not reported.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)