FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Rac2, Pak3
FlyBase ID
FBig0000098296
Interaction Network
Interactions Browser links
Rac2 network
Pak3 network
Reported Interactions
FBrf0187582-3.coIP.WB
Reference
Mentzel and Raabe, 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Rac2 

DmRAC2

bait

Myc tag

Pak3 

DmPAK3

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Pak3 binds to the activated form of Rac2.

(Mentzel and Raabe, 2005)

Pak3 binds to Rac1, Rac2 and weakly to Cdc42, but not to other RhoGTPases tested (Mtl, Rho1 or RhoL).

(Mentzel and Raabe, 2005)

Source was cell extract of HEK293 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Mentzel and Raabe, 2005)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)