FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
dpr12, DIP-δ
FlyBase ID
FBig0000098508
Interaction Network
Interactions Browser links
dpr12 network
DIP-δ network
Reported Interactions
FBrf0222867-136.ELISA
Reference
Ozkan et al., 2013
Description
physical association
Assay
Collection
ECIA
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
DIP-δ 

CG34391

bait

Fc tag

DIP-δ 
dpr12 

dpr12

prey

alkaline phosphatase tag, COMP pentamerization motif

dpr12 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
DIP-δ 
extracellular domain
sufficient binding region
dpr12 
extracellular domain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait derived from conditioned media of transfected S2 cell line; prey derived from conditioned media of transfected S2 cell line.

(Ozkan et al., 2013)
FBrf0222867-50.ELISA
Reference
Ozkan et al., 2013
Description
physical association
Assay
Collection
ECIA
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
dpr12 

dpr12

bait

Fc tag

dpr12 
DIP-δ 

CG34391

prey

alkaline phosphatase tag, COMP pentamerization motif

DIP-δ 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
dpr12 
extracellular domain
sufficient binding region
DIP-δ 
extracellular domain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait derived from conditioned media of transfected S2 cell line; prey derived from conditioned media of transfected S2 cell line.

(Ozkan et al., 2013)
FBrf0230454-40.ELISA
Reference
Carrillo et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
dpr12 

dpr12

bait

Fc tag

DIP-δ 

DIP-δ

prey

alkaline phosphatase tag, COMP pentamerization motif

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait derived from conditioned media of transfected S2 cell line; prey derived from conditioned media of transfected S2 cell line.

(Carrillo et al., 2015)
FBrf0230454-97.ELISA
Reference
Carrillo et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
DIP-δ 

DIP-δ

bait

Fc tag

dpr12 

dpr12

prey

alkaline phosphatase tag, COMP pentamerization motif

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait derived from conditioned media of transfected S2 cell line; prey derived from conditioned media of transfected S2 cell line.

(Carrillo et al., 2015)
FBrf0241075-27.SPR
Reference
Cosmanescu et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
DIP-δ 

DIP-δ

bait
DIP-δ 
dpr12 

Dpr12

prey
dpr12 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
DIP-δ 
extracellular domain
sufficient binding region
aa 42-143

coordinates relative to DIP-δ-PD

dpr12 
extracellular domain
sufficient binding region
aa 72-285

coordinates relative to dpr12-PC

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in HEK293F cells; prey produced as a recombinant fusion protein in HEK293F cells.

(Cosmanescu et al., 2018)

Kd = 2.44uM

(Cosmanescu et al., 2018)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)