FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
DCP1, Edc3
FlyBase ID
FBig0000098547
Interaction Network
Interactions Browser links
DCP1 network
Edc3 network
Reported Interactions
FBrf0203000-1.coIP.WB
Reference
Tritschler et al., 2007
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
DCP1 

DCP1

bait

HA tag

Edc3 

EDC3

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Tritschler et al., 2007)
FBrf0203000-3.coIP.WB
Reference
Tritschler et al., 2007
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Edc3 

EDC3

bait

HA tag

Edc3 
Edc3 
DCP1 

DCP1

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Edc3 
LSM domain
sufficient binding region
aa 1-101
Edc3 
LSM domain
mutation decreasing interaction
aa 25aa 42,44

Q25A

F42A, N44A

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Tritschler et al., 2007)
FBrf0206982-4.coIP.WB
Reference
Tritschler et al., 2008
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
DCP1 

DCP1

bait

HA tag

Edc3 

EDC3

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Tritschler et al., 2008)
FBrf0206982-7.coIP.WB
Reference
Tritschler et al., 2008
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Edc3 

EDC3

bait

HA tag

DCP1 

DCP1

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Tritschler et al., 2008)
FBrf0215100-2.coIP.WB
Reference
Zekri et al., 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Edc3 

EDC3

bait

GFP tag

DCP1 

DCP1

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Positive control.

(Zekri et al., 2009)

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Zekri et al., 2009)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)