Various loqs isoforms can interact with each other to for loqs homodimers or heterodimers.

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from transfected construct.

When an antibody specific to isoform loqs-PD was used for IP, interactions between endogenous loqs-PD and Myc-tagged overexpressed loqs isoforms -PB, -PC and -PD were detected. When the same antibody was used to IP endogenous loqs, isoform -PD was detected the most strongly, while other isoforms were detected very weakly or not at all. Similarly, when an antibody specific to isoform loqs-PB was used to IP endogenous loqs, isoform -PB was detected most strongly.

Interaction in vitro; protein produced as a recombinant fusion protein in bacterial system.

loqs homodimerizes.