FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Dscam2
FlyBase ID
FBig0000098734
Interaction Network
Interactions Browser links
Dscam2 network
Reported Interactions
FBrf0202429-2.coIP.WB
Reference
Millard et al., 2007
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Dscam2 

Dscam2

bait

Fc tag

Dscam2 

Dscam2

prey

FLAG tag

Dscam2 
Dscam2 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Dscam2 
extracellular domain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Fc-tagged Dscam2 was collected from S2 cell conditioned medium, and incubated with a separate cell extract from S2 cells expressing FLAG-tagged Dscam2.

(Millard et al., 2007)

Dscam2 exhibits isoform-specific homophilic binding. Dscam2 does not bind Dscam1 or Dscam3.

(Millard et al., 2007)

Interaction in vitro; bait derived from conditioned medium of transfected S2 cells; prey derived from transfected S2 cell line extract.

(Millard et al., 2007)
FBrf0222867-4.ELISA
Reference
Ozkan et al., 2013
Description
physical association
Assay
Collection
ECIA
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Dscam2 

Dscam2-PI

bait

Fc tag

Dscam2 

Dscam2-PI

prey

alkaline phosphatase tag, COMP pentamerization motif

Dscam2 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Dscam2 
extracellular domain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait derived from conditioned media of transfected S2 cell line; prey derived from conditioned media of transfected S2 cell line.

(Ozkan et al., 2013)
FBrf0222867-8.ELISA
Reference
Ozkan et al., 2013
Description
physical association
Assay
Collection
ECIA
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Dscam2 

Dscam2-PG

bait

Fc tag

Dscam2 

Dscam2-PG

prey

alkaline phosphatase tag, COMP pentamerization motif

Dscam2 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Dscam2 
extracellular domain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait derived from conditioned media of transfected S2 cell line; prey derived from conditioned media of transfected S2 cell line.

(Ozkan et al., 2013)
External Crossreferences and Linkouts ( 0 )
References (2)