FB2026_03 , released September 17, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000098755
Interaction Network
Interactions Browser links
sns network
unc-5 network
Reported Interactions
FBrf0222007-198.SPR
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

Unc-5

neutral component

His tag

Unc-5

neutral component

His tag

Unc-5

neutral component

His tag

sns 

SNS

neutral component

His tag

sns 
sns 

SNS

neutral component

His tag

sns 

SNS

neutral component

His tag

sns 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
extracellular domain
sufficient binding region
sns 
extracellular domain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; proteins produced and purified from baculovirus-infected High Five cells.

Kd = 5E10-4 M

FBrf0222867-183.ELISA
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sns 

sns

bait

Fc tag

sns 

unc-5

prey

alkaline phosphatase tag, COMP pentamerization motif

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
sns 
extracellular domain
sufficient binding region
extracellular domain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait derived from conditioned media of transfected S2 cell line; prey derived from conditioned media of transfected S2 cell line.

FBrf0222867-97.ELISA
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

unc-5

bait

Fc tag

sns 

sns

prey

alkaline phosphatase tag, COMP pentamerization motif

sns 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
extracellular domain
sufficient binding region
sns 
extracellular domain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait derived from conditioned media of transfected S2 cell line; prey derived from conditioned media of transfected S2 cell line.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)