FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Lhr, Cenp-C
FlyBase ID
FBig0000100642
Interaction Network
Interactions Browser links
Lhr network
Cenp-C network
Reported Interactions
FBrf0223436-16.coIP.MS
Reference
Thomae et al., 2013
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Lhr 

LHR

bait

Myc tag

Cenp-C 

Cenp-C

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Cenp-C was observed in Hmr or tandem Hmr-Lhr affinity purification experiments, but not in single Lhr affinity purifications.

(Thomae et al., 2013)

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Thomae et al., 2013)

Purified FLAG-Hmr complexes were subjected to additional purification of Myc-tagged Lhr.

(Thomae et al., 2013)
FBrf0223436-6.coIP.WB
Reference
Thomae et al., 2013
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Lhr 

LHR

bait
Cenp-C 

Cenp-C

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Thomae et al., 2013)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)