FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Grip, fz2
FlyBase ID
FBig0000103173
Interaction Network
Interactions Browser links
Grip network
fz2 network
Reported Interactions
FBrf0195116-1.coIP.WB
Reference
Ataman et al., 2006
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
fz2 

DFz2

bait

Myc tag

Grip 

dGRIP

prey

V5 tag

Grip 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Grip 
PDZ 4,5
sufficient binding region
aa 431-747
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Ataman et al., 2006)
FBrf0195116-2.Y2H
Reference
Ataman et al., 2006
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Grip 

Grip

bait

fused to LexA DNA-binding domain

Grip 
fz2 

DFz2

prey

fused to GAL4 activation domain

fz2 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Grip 
PDZ 4,5
sufficient binding region
aa 431-747
fz2 
C terminal region
sufficient binding region
aa 610-698
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Ataman et al., 2006)

Two-hybrid system: yeast LexA-BD/GAL4-AD

(Ataman et al., 2006)
FBrf0211361-3.coIP.WB
Reference
Mosca and Schwarz, 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
fz2 

DFz2

bait

Myc tag

Grip 

dGRIP

prey

V5 tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Mosca and Schwarz, 2010)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)