FB2025_05 , released December 11, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Cyfip, Chc
FlyBase ID
FBig0000103767
Interaction Network
Interactions Browser links
Cyfip network
Chc network
Reported Interactions
FBrf0216441-5.coIP.MS
Reference
Gautier et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Cyfip 

Sra1

bait
Chc 

CHC

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Chc is identified in Sra-1 immunoprecipitation by mass spectroscopy and Chc RNAi produces SCAR-like phenotypes in S2R+ cells. This interaction is conserved in human HeLa cells.

(Gautier et al., 2011)

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Gautier et al., 2011)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)