FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
casp, Sumo
FlyBase ID
FBig0000103818
Interaction Network
Interactions Browser links
casp network
Sumo network
Reported Interactions
FBrf0229794-25.PD.WB
Reference
Handu et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
casp 

casp

bait

GST tag

casp 
Sumo 

SUMO

prey

His tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
casp 
interaction domain
mutation disrupting interaction
aa 551

K551R

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Mutation K362R in casp demonstrates no disruption in interaction.

(Handu et al., 2015)

Interaction in vivo; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Handu et al., 2015)
FBrf0229794-26.PD.WB
Reference
Handu et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Sumo 

SUMO

bait

His tag

casp 

casp

prey

GST tag

casp 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
casp 
interaction domain
mutation disrupting interaction
aa 551

K551R

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Mutation K362R in casp demonstrates no disruption in interaction.

(Handu et al., 2015)

Interaction in vivo; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Handu et al., 2015)
FBrf0229794-27.coIP.WB
Reference
Handu et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
casp 

casp

bait

HA tag

Sumo 

SUMO

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Handu et al., 2015)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)