FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000103869
Interaction Network
Interactions Browser links
Cka network
pll network
Reported Interactions
FBrf0230801-1.coIP.WB
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Cka 

Cka

bait

FLAG tag

pll 

Pll

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

pll interacts with Cka but not other members of the STRIPAK complex (Slmap, Fgop2, Strip or Mob4).

Increased pll levels lead to phosphorylation of Cka with subsequent Cka degradation.

FBrf0230801-2.ENZ.WB
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Cka 

Cka

enzyme
Cka 

Cka

enzyme
pll 

Pll

enzyme target

GST tag

pll 

Pll

enzyme target

GST tag

pll 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)