FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
spn-F
FlyBase ID
FBig0000104068
Interaction Network
Interactions Browser links
spn-F network
Reported Interactions
FBrf0230080-1.coIP.WB
Reference
Lin et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
spn-F 

Spn-F

bait

FLAG

spn-F 

Spn-F

prey

myc

spn-F 
spn-F 
spn-F 
spn-F 
spn-F 
spn-F 
spn-F 
spn-F 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
spn-F 
interaction residue 53
mutation decreasing interaction
aa 53

mutation to 53D

spn-F 
interaction residue 85
mutation decreasing interaction
aa 85

mutation to 85D

spn-F 
interaction residue 172
mutation decreasing interaction
aa 172

mutation to 172D

spn-F 
interaction residue 202
mutation decreasing interaction
aa 202

mutation to 202D

spn-F 
interaction residue 246
mutation decreasing interaction
aa 246

mutation to 246D

spn-F 
interaction residue 270
mutation decreasing interaction
aa 270

mutation to 270D

spn-F 
interaction residue 325
mutation decreasing interaction
aa 325

mutation to 325D

spn-F 
interaction residue 349
mutation decreasing interaction
aa 349

mutation to 349D

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Lin et al., 2015)

Addition of IKKε decreases the self-association of spn-F proteins.

(Lin et al., 2015)
External Crossreferences and Linkouts ( 0 )
References (1)