FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
inaD, kon
FlyBase ID
FBig0000104162
Interaction Network
Interactions Browser links
inaD network
kon network
Reported Interactions
FBrf0214003-1.FPS
Reference
Liu et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
inaD 

INAD

bait
inaD 
kon 

Kon

prey
kon 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
inaD 
PDZ5 domain
sufficient binding region
aa 580-665

coordinates relative to inaD-PA

kon 
region
sufficient binding region
LLRRNQYWV
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey peptide chemically synthesized and labeled in vitro.

(Liu et al., 2011)

The inaD PDZ5 domain binds kon peptide with Kd = 1.3uM. Oxidation of the inaD PDZ5 domain reduces affinity for kon (Kd = 20.4uM).

(Liu et al., 2011)
FBrf0214003-2.NMR
Reference
Liu et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
inaD 

INAD

neutral component
inaD 

INAD

neutral component
inaD 
inaD 

INAD

neutral component
inaD 
kon 

Kon

neutral component
kon 
kon 

Kon

neutral component
kon 

Kon

neutral component
kon 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
inaD 
PDZ5 domain
sufficient binding region
aa 580-665

coordinates relative to inaD-PA

kon 
region
sufficient binding region
LLRRNQYWV
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey peptide chemically synthesized and labeled in vitro.

(Liu et al., 2011)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)