FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Vang, dgo
FlyBase ID
FBig0000104168
Interaction Network
Interactions Browser links
Vang network
dgo network
Reported Interactions
FBrf0180143-2.PD.A
Reference
Das et al., 2004
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
dgo 

Dgo

bait

GST tag

dgo 
Vang 

Stbm

prey

[35]S label

Vang 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
dgo 
ankryin repeats
sufficient binding region
aa 1-263

aa coordinates inferred from primer sequences.

Vang 
cytoplasmic tail domain
necessary binding region
aa 361-444

aa coordinates inferred from citation FBrf0162094

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

(Das et al., 2004)
FBrf0245453-4.coIP.WB
Reference
Humphries et al., 2020
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Vang 

Vang

bait

FLAG tag

Vang 
Vang 
dgo 

Dgo

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Vang 
interaction domain
sufficient binding region
aa 1-319

coordinates relative to Vang-PA

Vang 
interaction domain
necessary binding region
aa 300-319

coordinates relative to Vang-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Humphries et al., 2020)
FBrf0257118-3.coIP.WB
Reference
Humphries et al., 2023
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Vang 

Vang

bait

FLAG tag

dgo 

dgo

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Humphries et al., 2023)

positive control

(Humphries et al., 2023)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)