FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
mrj, Hrb98DE
FlyBase ID
FBig0000104361
Interaction Network
Interactions Browser links
mrj network
Hrb98DE network
Reported Interactions
FBrf0231072-1.coIP.WB
Reference
Li et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
mrj 

MRJ

bait

FLAG tag

mrj 
Hrb98DE 

Hrb98DE

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
mrj 
residue F101
mutation disrupting interaction
aa 101

F101I, coordinates relative to mrj-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

The F101I mutation of fly mrj is a "disease-homologous mutation" - it corresponds to the F89I mutation of Hsap\DNAJB6 found in patients with limb-girdle muscular dystrophy type 1E (LGMD1E).

(Li et al., 2016)

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Li et al., 2016)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)