FB2025_01 , released February 20, 2025
Physical Interaction report
Open Close
General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000104444
Interaction Network
Interactions Browser links
Vang network
fz network
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0206051-1.PD.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
fz 

Fz

bait

AP tag

fz 
fz 
fz 
Vang 

Vang

prey

YFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
fz 
extracellular region
sufficient binding region
fz 
cystein rich domain
necessary binding region
fz 
cystein rich domain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait and prey produced as a recombinant fusion protein in cell culture.

sm does not interact with Vang in this experiment.

FBrf0206051-2a.AT.AP
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Vang 

Vang

bait

YFP tag

fz 

Fz

prey

AP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced from transfected construct; prey derived from conditioned media of transfected S2 cells.

Cells expressing Vang were incubated with the extracellular domain of fz fused to alkaline phosphatase (AP). Binding was inferred by the amount of AP bound to the cell surface of cells.! IN8a. Public comments :

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)