AGO3, but not aub, coimmunoprecipitates armi. The AGO3-armi interaction is enriched in mitochondrial fractions. The AGO3-armi interaction is enhanced when zuc is knocked down by RNAi, possibly due to higher armi protein levels.

Source was adult female ovaries of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

Source was adult female ovaries of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

armi binds more strongly to an AGO3 mutant that lacks slicer activity. While the AGO3-armi interaction is enriched in mitochondrial fractions, interaction of armi with the slicer mutant is enriched in cytosolic fractions.