FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Seipin
FlyBase ID
FBig0000105139
Interaction Network
Interactions Browser links
Seipin network
Reported Interactions
FBrf0224947-4.coIP.WB
Reference
Bi et al., 2014
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Seipin 

dSeipin

bait

Myc tag

Seipin 

dSeipin

prey

FLAG tag

Seipin 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Seipin 
loop region
necessary binding region
aa 88-250
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Bi et al., 2014)

Seipin self-oligomerizes.

(Bi et al., 2014)
FBrf0240742-1.EM
Reference
Sui et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Seipin 

seipin

neutral component
Seipin 

seipin

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; protein produced as a recombinant fusion protein in bacterial system.

(Sui et al., 2018)

Seipin forms a dodecamer.

(Sui et al., 2018)
External Crossreferences and Linkouts ( 0 )
References (2)