FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
morgue, Diap1
FlyBase ID
FBig0000105185
Interaction Network
Interactions Browser links
morgue network
Diap1 network
Reported Interactions
FBrf0149131-1.coIP.WB
Reference
Hays et al., 2002
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
morgue 

Morgue

bait

FLAG tag

Diap1 

Diap1

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Hays et al., 2002)

Removal of the UBC domain of morgue did not disrupt the interaction with Diap1. The Diap1 RING finger domain is not required for its interaction with morgue.

(Hays et al., 2002)
FBrf0149131-2.coIP.WB
Reference
Hays et al., 2002
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Diap1 

DIAP1

bait

HA tag

morgue 

Morgue

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Hays et al., 2002)
FBrf0149135-3.PD.A
Reference
Wing et al., 2002
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
morgue 

Morgue

bait

GST tag

Diap1 

DIAP1

prey

[35]S label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

morgue interaction with Diap1 is independant of the morgue F-box.

(Wing et al., 2002)

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

(Wing et al., 2002)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)