FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
insv, Cp190
FlyBase ID
FBig0000105289
Interaction Network
Interactions Browser links
insv network
Cp190 network
Reported Interactions
FBrf0227658-1.coIP.WB
Reference
Dai et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
insv 

Insv

bait

V5 tag

Cp190 

CP190

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Dai et al., 2015)
FBrf0241011-4.Y2H
Reference
Fedotova et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
insv 

Insv

bait

fused to GAL4 DNA-binding domain

insv 
insv 
Cp190 

CP190

prey

fused to GAL4 activation domain

Cp190 
Cp190 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
insv 
N-terminal domain
sufficient binding region
aa 1-157
insv 
interaction domain
necessary binding region
aa 135-150
Cp190 
BTB domain
sufficient binding region
aa 1-166
Cp190 
M domain
sufficient binding region
aa 309-470
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Fedotova et al., 2019)

Two-hybrid system: yeast GAL4-BD/GAL4-AD

(Fedotova et al., 2019)
FBrf0241011-5.PD.MW
Reference
Fedotova et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
insv 

Insv

bait

MBP tag

insv 
Cp190 

CP190

prey

His tag

Cp190 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
insv 
N-terminal domain
sufficient binding region
aa 1-267
Cp190 
BTB domain
sufficient binding region
aa 1-126
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

(Fedotova et al., 2019)
FBrf0241011-6.PD.MW
Reference
Fedotova et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Cp190 

CP190

bait

His tag

Cp190 
insv 

Insv

prey

TRX tag

insv 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
insv 
N-terminal domain
sufficient binding region
aa 1-267
Cp190 
BTB domain
sufficient binding region
aa 1-126
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

(Fedotova et al., 2019)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)