FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Myd88, wek
FlyBase ID
FBig0000105795
Interaction Network
Interactions Browser links
Myd88 network
wek network
Reported Interactions
FBrf0193565-5.coIP.WB
Reference
Chen et al., 2006
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Myd88 

MyD88

bait

V5 tag

wek 

Wek

prey

HA tag

wek 
wek 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
wek 
middle region
sufficient binding region
aa 104-272

"wekM" construct, coordinates relative to wek-PA

wek 
C-terminal region
sufficient binding region
aa 273-470

"wekC" construct, coordinates relative to wek-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Chen et al., 2006)

All Myd88 truncations tested disrupt wek binding.

(Chen et al., 2006)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)