FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
scrib
FlyBase ID
FBig0000105836
Interaction Network
Interactions Browser links
scrib network
Reported Interactions
FBrf0233965-4.coIP.WB
Reference
Gui et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
scrib 

Scrib

bait

RFP tag

scrib 

Scrib

prey

Myc tag

scrib 
scrib 
scrib 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
scrib 
LRR domain
sufficient binding region
aa 1-692

"LRR" construct, coordinates relative to scrib-PA

scrib 
PDZ3-4
sufficient binding region
aa 928-1400

"PDZ3-4" construct, coordinates relative to scrib-PA

scrib 
C-terminal region
sufficient binding region
aa 1338-1756

"CT" construct, coordinates relative to scrib-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Gui et al., 2016)

The LRR domain of scrib can bind to itself or other regions of scrib.

(Gui et al., 2016)
External Crossreferences and Linkouts ( 0 )
References (1)