FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
mir-279, gcm
FlyBase ID
FBig0000105854
Interaction Network
Interactions Browser links
mir-279 network
gcm network
Reported Interactions
FBrf0220777-1.miR-mRNA.WB
Reference
Laneve et al., 2013
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
mir-279 

mir-279

bait
gcm 

Gcm

prey
gcm 
gcm 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
gcm 
3-prime UTR
sufficient binding region
gcm 
mir-279 target site
necessary binding region
AGCGUUGUUCUAGUC
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected reporter construct.

(Laneve et al., 2013)

Overexpression of mir-279 reduces gcm protein levels.

(Laneve et al., 2013)
FBrf0220777-2.miR-mRNA.WB
Reference
Laneve et al., 2013
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage 11
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-279 

mir-279

bait
gcm 

Gcm

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Overexpression of mir-279 reduces endogenous gcm protein levels.

(Laneve et al., 2013)

Source was embryos of transgenic fly line; bait produced from transfected construct; prey produced from endogenous gene.

(Laneve et al., 2013)
FBrf0220777-3.miR-mRNA.PCR
Reference
Laneve et al., 2013
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage 11
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-279 

mir-279

bait
gcm 

Gcm

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Overexpression of mir-279 reduces endogenous gcm mRNA levels.

(Laneve et al., 2013)

Source was embryos of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

(Laneve et al., 2013)
FBrf0220777-4.miR-mRNA.LUC.PCR
Reference
Laneve et al., 2013
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage 11
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-279 

mir-279

bait
gcm 

Gcm

prey
gcm 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
gcm 
3-prime UTR
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Level of luciferase reporter assayed by RT-PCR.

(Laneve et al., 2013)

Source was embryos of transgenic fly line; bait produced from transgenic construct; prey produced from transgenic construct.

(Laneve et al., 2013)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)