FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Diap2, hid
FlyBase ID
FBig0000106482
Interaction Network
Interactions Browser links
Diap2 network
hid network
Reported Interactions
FBrf0192581-5.PD.WB
Reference
Leulier et al., 2006
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
hid 

Hid

bait

GST tag

Diap2 

DIAP2

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from S2 cell extract.

(Leulier et al., 2006)
FBrf0192581-7.PD.WB
Reference
Leulier et al., 2006
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Diap2 

DIAP2

bait

GST tag

hid 

HID

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from S2 cell extract.

(Leulier et al., 2006)
FBrf0201142-4.PD.WB
Reference
Ribeiro et al., 2007
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Diap2 

DIAP2

bait

GST tag

Diap2 
Diap2 
hid 

Hid

prey

V5 tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Diap2 
BIR domains
sufficient binding region
aa 1-338
Diap2 
BIR domains residues 149,249
mutation decreasing interaction
aa 149,249

C149G, C249G

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced from transfected HEK293T cells.

(Ribeiro et al., 2007)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)